Bite of a aedes aegypti mosquito carrying a virus
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Virus goes into the circulation
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Infects cells & generate cellular response
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Initiates destruction of the platelet
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↑ Potential for hemorrhage
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Stimulates intense inflammatory response
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Fever, vascular response, redness and heat
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Shivering, chills from muscle contraction and blood vessel constriction
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Headache, vomiting, epistaxis, abdominal pain, circulatory collapse shock
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Death